Modafinil is a powerful mind performance enhancer reported to offer impressive cognitive benefits in even otherwise healthy adults [ 2 ]. Some of these are frequently reported to include:. But first, know that there are some potential trade-offs when taking this potent compound. Modafinil is sold under a variety of brand names and is typically available in mg and mg tablet form.
The standard prescription dose to help promote wakefulness in people with sleep disorders is mg daily, taken once a day with or without food. Whereas narcolepsy and obstructive sleep apnea patients usually take their dose in the morning, SWSD patients are typically directed to take it one hour prior to starting their shift.
If you have been prescribed modafinil, simply use it as directed by your physician. On the non-medical side of things, nootropics users reporting taking modafinil doses anywhere from 50 mg per day to mg per day. For more information on how nootropics users have chosen the doses that work best for them, check out our modafinil dosage guide. There are a variety of circumstances in which modafinil use should be avoided or very closely monitored.
For example, physicians often consider the following circumstances or conditions as reasons to not prescribe modafinil [ 5 , 6 ]:. When starting the drug, it is equally important to monitor for allergic reactions, skin rashes and blood pressure. While modafinil has a low risk of dependence and is generally non-addictive [7], make sure to see a doctor if you think you may have become mentally or physically dependent on it.
It is generally advisable to avoid all other medicines, supplements, alcohol and caffeine while modafinil is still in your system.
Based on a study into the use of modafinil as a wakefulness promoter for military aviators, Modafinil is well tolerated at doses of mg per day [ 8 ].
Fortunately, we find that these side effects may be minimized or eliminated by taking a few simple precautions, including taking modafinil in the early morning, drinking plenty of water and making sure to follow a regular eating schedule. Other modafinil side effects and safety concerns include [ 9 ]:. While this goes without saying, if you develop chest pains you must seek medical attention immediately.
In our experience, the vast majority of healthy modafinil users experience relatively mild, if any, side effects when taking the drug. Generally speaking, modafinil causes levels of histamine in the brain to rise, causing extreme alertness in the user [ 10 ] and preventing feelings of sleepiness or fatigue [ 11 ].
Modafinil also enhances working and episodic memory [ 12 ] by increasing the amounts of dopamine, serotonin and norepinephrine in the brain [ 13 ]. This mechanism lets the user think more clearly and work more effectively, even if they are stressed or are under a lot of pressure. In other words, is there a lethal dosage for modafinil? As you can see, no bad outcomes — even at the mind-bogglingly high dosages administered. That said, there have been unconfirmed reports of fatal overdoses involving modafinil alone.
But we would question the veracity of such reports, since we could not fathom the quantity actually ingested. To our knowledge, nobody has ever been confirmed to ingest 12 grams of modafinil in a single day. The lesson: We see very little to be concerned about as far as modafinil overdose. In any case, users are well-advised to be smart and stick to their minimum effective modafinil dose.
This is because modafinil simultaneously induces and inhibits certain metabolic enzymes in the liver involved in the processing of these drugs [ 20 ]:. Moreover, modafinil is known to decrease the effectiveness of certain types of birth control and thereby increases the likelihood of pregnancy in patients otherwise taking birth control [ 21 ].
We would finally add that care be taken if taking blood pressure pills with modafinil, as the drug can counteract the activity of anti-hypertensive drugs. Modafinil can be harmful to your unborn baby, resulting in possible congenital disabilities. Modafinil can be harmful to babies and young children. Drug interactions with modafinil can lead to adverse side effects. Mixing modafinil with alcohol or other illicit drugs can lead to adverse side effects.
Some hormonal contraceptives may have lowered efficiency when using modafinil. These contraceptive methods include birth control pills, injections, hormonal implants and patches, vaginal rings, and intrauterine contraceptive devices IUD. A woman of childbearing age should take extra care in these cases if you do not wish to become pregnant. Modafinil is considered a strong stimulant, and if a person takes an excessive amount of modafinil, it could lead to bodily harm.
In addition, excessive intake of stimulants leads to more risky and unpredictable behavior, hallucinations, and impaired judgment. In people who have a pre-existing mental illness, diagnosed or not, stimulant abuse can cause a manic episode or psychosis, which requires hospitalization to treat and manage the condition.
Modafinil, if abused, can end in a psychological dependence or a physical addiction. Due to this possibility for abuse, it is classified as part of the schedule IV drugs. However, stimulant dependency can easily be managed with cognitive behavioral therapy CBT and counselling. If you suspect that a modafinil overdose has occurred, contact the poison control center immediately for medical assistance and follow their instructions.
Due to the way modafinil is packaged, it's not easy to accidentally overdose on modafinil. Modafinil dosages are pre-packed in pill consistency for your convenience. Always take your medication as indicated on your modafinil prescription from a medical doctor to prevent adverse side effects or an accidental overdose.
To date, no modafinil related fatalities have been reported. Likewise, no evidence suggests modafinil overdoses could result in death. Modafinil is available in mg and mg tablets. However, evidence-based research revealed the ideal dosage for most people is mg modafinil once a day in treating sleep disorders.
For example, the recommended modafinil dosage in the treatment for narcolepsy and OSA is mg modafinil once a day. Modafinil dosage can be increased, but should not exceed mg per day. When treating shift work sleep disorder with modafinil, the recommended dosage is mg modafinil an hour before the start of the shift.
Modafinil dosages may vary from person to person; however, research suggests the ideal treatment dosage of modafinil is mg. Modafinil dosages should be gradually increased or decreased to avoid any adverse effects.
Always discuss taking modafinil or other similar medications with your healthcare provider before taking these. Modafinil or generic medications of modafinil are widely available and easy to come by in most countries. However, there are different ways through which you can acquire modafinil and its generic versions, depending on the laws and regulations of your country.
In some Western countries, like the United States, Canada, United Kingdom, and Australia, it would be best to have a valid doctor's prescription to buy modafinil from retail pharmacies or local pharmacies. You cannot purchase modafinil as an over the counter medication. In these Western countries, it is not illegal to possess modafinil, as long as it is only consumed for personal use purposes.
Countries where you can buy modafinil without a prescription include Mexico, Colombia, India, Peru, and Ecuador. Here you can easily buy modafinil over the counter at your local pharmacy or from a local vendor. Purchasing modafinil online has never been easier.
Buying modafinil online gives you the freedom to decide if you want the original modafinil brands or generic modafinil brands. Additionally, you can easily compare modafinil prices for popular generic brands. First and foremost, when you buy modafinil online, make sure that it is high-quality modafinil from a trusted source. Tags: Paid Content , Sponsored Content. We welcome readers to submit letters regarding articles and content in Cleveland Scene. Letters should be a minimum of words, refer to content that has appeared on Cleveland Scene , and must include the writer's full name, address, and phone number for verification purposes.
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Email us at news clevescene. Local journalism is information. Information is power. And we believe everyone deserves access to accurate independent coverage of their community and state. Our readers helped us continue this coverage in , and we are so grateful for the support. Help us keep this coverage going in Introduction and aims: Prescription medications are readily accessible on both the dark and surface web.
This study focuses specifically on modafinil. Modafinal is a medication that is used to treat sleepiness due to a range of sleep disorders, but is also used off-label as a cognitive enhancer. This study aimed to evaluate surface websites which sold modafinil to Australia to provide an overview of and to document the characteristics of surface web retailers.
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